Photonic Biosensors

At a Glance

Low-cost, single-use disposable sensor with multiple sensing channels, each sensitized to detect different chemical or biological substances. 

Technical Background

At Fraunhofer HHI, a photonic sensor technology has been developed that allows simultaneous, highly sensitive real-time measurements of chemical or biological parameters. 

Substance concentrations can be determined without markers in liquid or gaseous analytes, thanks to the functionalization of the sensor surface. Microring sensors can be combined on a sensor chip for use in multi-parameter analytics in Point-of-Care testing. 

  • Measurement of refractive index via shift of optical resonances
  • Cascading of sensor elements
  • Multiplexing enables multi-parameter analysis
  • Functionalization of individual sensor elements enables specific detection 

Features 

  • Fast label-free multiplex analysis
  • Point-of-Care
  • Cost-effective 
  • Resource-efficient
  • Low sample volume
  • Multiple sensor elements per chip through multiplexing 
  • Hundreds of sensor chips on each wafer 
  • Operates as a label-free biosensor with a detection limit > 100nm/RIU and in < pmol/µl range (for proteins)
  • Low sample volume of < 30µl
  • Can target proteins, small molecules, vitamins, viruses, bacteria and nucleic acids
  • Highly integrable system, also with microfluidics 

Applications

  • Medical
  • Companion diagnostics 
  • Environmental analysis
  • Food industry
  • Water analytics

 

Silicon Nitride Wafer
Eight Channel Photonic Sensor Chip
Optical Multi-Sensor Device
Microfluidics