Predicting the binding of viral peptides to the major histocompatibility complex with machine learning can potentially extend the computational immunology toolkit for vaccine development, and serve as a key component in the fight against a pandemic. In this work, we adapt and extend USMPep, a recently proposed, conceptually simple prediction algorithm based on recurrent neural networks. Most...

We measured and simulated the radiation pattern of continuous-wave terahertz emitters between 100 and 500 GHz. We could improve the radiation pattern by optimizing the connection between terahertz source and antenna: Unwanted side lobes were reduced by more than 10 dB and the beam angle was narrowed to 9° at 300 GHz. These improvements are relevant for wireless...

We present a hybrid animation approach that combines example-based and neural animation methods to create a simple, yet powerful animation regime for human faces. We introduce a light-weight auto-regressive network to transform our animation-database into a parametric model. During training, our network learns the dynamics of facial expressions, which enables the replay of annotated sequences...

With the goal of enabling optical wireless communications for mobile devices, we assess a physical layer based on high-bandwidth on-off keying modulation. This allows for amplifier designs that avoid operation in a resistive mode, reducing their energy usage to a fraction. Link-level simulations show that the investigated physical layer can deal with typical frontend limitations and can...

This paper provides a timely overview of the field of explainable artificial intelligence (XAI). It explains the theoretical foundations of interpretability algorithms, outlines best practice aspects, demonstrates successful usage of XAI in selected application scenarios, and discusses challenges and possible future directions of this active emerging field.

This paper proposes a novel approach for coherent detection with double-side vertically illuminated photodetectors. Signal and local oscillator are injected collinearly from opposite sides of the photodetector chip. The concept inherently provides angular selective detection and can be used for developing compact, solid-state receiver modules for coherent light detection and ranging (LiDAR)....

Electrical impedance tomography (EIT) is a non-invasive imaging modality that allows a continuous assessment of changes in regional bioimpedance of different organs. One of its most common biomedical applications is monitoring regional ventilation distribution in critically ill patients treated in intensive care units. In this work, we put forward a proof-of-principle study that demonstrates...

Time-domain spectroscopy with terahertz frequencies typically requires complex and bulky systems. Here, the authors present an optoelectronics-based, frequency-domain terahertz sensing technique which offers competitive measurement performance in a much simpler system.

This paper proposes a novel criterion for CNN pruning inspired by neural network interpretability: The most relevant units, i.e. weights or filters, are automatically found using their relevance scores obtained from concepts of explainable AI (XAI). By exploring this idea, we connect the lines of interpretability and model compression research.

This paper gives a comprehensive overview over classic shallow and novel deep approaches to anomaly detection. We identify the common underlying principles and provide an empirical assessment of major existing methods that are enriched by the use of recent explainability techniques. We present specific worked-through examples together with practical advice and discuss open challenges.

Inverse design is rapidly gaining popularity for automated design of photonic components. Two methods to improve it for large passive waveguide structures are developed: Adaptive Threshold Binarization and Hybrid Optimization. To demonstrate their capability, inverse design is applied to an InP waveguide platform for the first time. As an example, a polarizer with a PER of -19.4 dB is...

This paper proposes a novel, simple yet effective defense strategy for adversarial attacks on deep learning models. Our algorithm, called MALA for DEfense (MALADE), is applicable to any existing classifier, providing robust defense as well as off-manifold sample detection. In our experiments, MALADE exhibited state-of-the-art performance against various elaborate attacking strategies.